Recent Publications
1. Palmer, Raymond F., David Kattari, Rodolfo Rincon, and Claudia S. Miller. 2024. “Assessing Chemical Intolerance in Parents Predicts the Risk of Autism and ADHD in Their Children” Journal of Xenobiotics 14, no. 1: 350-367. https://doi.org/10.3390/jox14010022
2. Johnson-Esparza Y, Wood R, Cruz I, & Palmer, R. (In press). Diabetes quality of life, chemical intolerance, and generational status in a Latino sample: an RRNeT study. Journal of Diabetes & Metabolic Disorders.
This study highlights generational differences in the impact of diabetes and chemical intolerance on quality of life. Latino immigrants were less likely to have scores indicative of chemical intolerance as compared to U.S.-born Latinos. This is the first studies to understand the impact of chemical intolerance on chemical intolerance in the context of a chronic condition such as type 2 diabetes.
3. Palmer RF, Almeida M, Rincon R, Perales RB. (2023) A genome-wide SNP investigation of chemical intolerance. Environmental Advances, https://doi.org/10.1016/j.envadv.2023.100380. We identified several novel gene markers associated with chemical Intolerance. These genes are associated with many comorbidities of Chemical Intolerance.
4. Miller CS, Palmer RF, Kattari D, et al., (2023) What initiates chemical intolerance? Findings from a large population‑based survey of U.S. adults. Chemical Intolerance. Environmental Sciences Europe 35:65, https://doi.org/10.1186/s12302-023-00772-x This large population study identified mold, pesticides, remodeling/new construction, medical/surgical procedures, fires/combustion products as well as protracted antibiotic use as primary initiators of chemical intolerance.
5. Palmer RF, Dempsey TT, Afrin LB. (2023) Chemical Intolerance and Mast Cell Activation: A Suspicious Synchronicity. Journal of Xenobiotics. 13, 704–718. https://doi.org/10.3390/jox13040045 A replication and confirmation of the first Mast Cell paper by Miller et al., (2021) indicating the potential role of Mast Cells affecting Chemical Intolerance.
6. Perales RB, Palmer RF, Rincon R, Viramontes JN, Walker T, Jaén CR, Miller CS. (2022) Does improving indoor air quality lessen symptoms associated with chemical intolerance? Primary Health Care Research & Development 23(e3): 1–12. This study describes the results of our Environmental House Calls demonstrating improved symptoms among those with chemical intolerance who improved the indoor air quality as a result of our recommendations.
7. Palmer, RF, Rincon R, Perales, RB, Walker T, Jaén C, Miller CS. (2022)The Brief Environmental Exposure and Sensitivity Inventory (BREESI): an International Validation study. Environmental Sciences Europe 34:32, https://doi.org/10.1186/s12302-022-00600-8 The study shows the effectiveness of this 3-item survey as a screener for Chemical Intolerance in 5 countries.
8. Palmer RF, Walker T, Perales RB, Rincon R, Jaén CR, Miller CS. (2021) Disease comorbidities associated with chemical intolerance. Environ Dis 2021;6:134-41. This paper reveals a list of chronic diseases reported by those with and without chemical intolerance. Those with chemical intolerance experience more chronic illnesses compared to those without chemical intolerance
9. Palmer, R.F.; Walker, T.; Kattari, D.; Rincon, R.; Perales, R.B.; Jaén, C.R.; Grimes, C.; Sundblad, D.R.; Miller, C.S. (2021) Validation of a Brief Screening Instrument for Chemical Intolerance in a Large U.S. National Sample. Int. J. Environ. Res. Public Health, 18, 8714. Our second demonstration that a brief 3-item survey is an excellent screener for chemical intolerance. This was tested in a US population sample of over 10,000 participants. Again, the BREESI correctly classified chemical intolerance 90% of the time. This is an excellent tool for screening chemical intolerance in epidemiological or other survey research.
10. Miller, C.S., Palmer, R.F., Dempsey, T.T. Ashford, N. (2021). Mast cell activation may explain many cases of chemical intolerance. Environ Sci Eur 33, 129 This paper provides for the first time a plausible biological mechanism for chemical intolerance. Overactive mast cells may be responsible for the various symptoms experienced by those with CI. Some dietary and medical interventions are discussed.
11. Masri S, Miller CS, Palmer RF, Ashford, N (2021)Toxicant-induced loss of tolerance for chemicals, foods, and drugs: assessing patterns of exposure behind a global phenomenon. Environ Sci Eur 33, 65 This study is a review of the chemical intolerance phenomena in terms of the exposures that can initiate the disease.
12. Palmer RF, Jae´n CR, Perales RB, Rincon R, Forster JN, Miller CS (2020) Three questions for identifying chemically intolerant individuals in clinical and epidemiological populations: The Brief Environmental Exposure and Sensitivity Inventory (BREESI). PLoS ONE 15(9): e0238296. Our first demonstration that a brief 3-item survey is an excellent screener for chemical intolerance. Used in our clinical study of 200 individuals, the BREESI correctly classified those with chemical intolerance when validated with our 50-item survey (QEESI). This is an excellent tool for screening chemical intolerance in a busy health care clinic.